NASDAQ : SEPN
Septerna, Inc. — Financial statements
Healthcare · Biotechnology · United States
Last price 44 USD (Oct 30, 2026, 4:00 PM EDT) · Market cap 2.05B
Overview · Financial statements · Key statistics · Dividends · Company profile · Price history · Reports
Financial statements
Septerna, Inc. (SEPN) reported revenue of 98.88M USD (TTM). Five years of income statement, balance sheet, cash flow and ratios below.
Income statement
Fiscal year January - December; amounts in USD.
| TTM | FY2025 | FY2024 | FY2023 | FY2022 | |
|---|---|---|---|---|---|
| Revenue | 98.88M | 45.95M | 1.07M | 151.00K | |
| Gross Profit | 98.88M | 45.95M | 1.07M | 151.00K | |
| Selling, General & Admin | 34.13M | 29.16M | 16.56M | 9.72M | 5.92M |
| Research & Development | 120.79M | 97.58M | 65.34M | 35.98M | 22.04M |
| Operating Expenses | 154.93M | 126.75M | 81.90M | 45.70M | 27.97M |
| Operating Income | -56.05M | -80.80M | -80.82M | -45.55M | -27.97M |
| Interest & Investment Income | 20.73M | 19.53M | 8.62M | 2.79M | 291.00K |
| Other Non Operating Income (Expenses) | -101.00K | -100.00K | -90.00K | 10.00K | |
| EBT Excluding Unusual Items | -35.41M | -61.37M | -72.30M | -42.75M | -27.68M |
| Gain (Loss) on Sale of Assets | 12.50M | 12.50M | 47.62M | ||
| Pretax Income | -22.91M | -48.87M | -72.30M | 4.87M | -27.68M |
| Income Tax Expense | 1.32M | 12.00K | -498.00K | 691.00K | |
| Net Income | -24.24M | -48.88M | -71.80M | 4.18M | -27.68M |
| Preferred Dividends & Other Adjustments | 3.61M | ||||
| Net Income to Common | -24.24M | -48.88M | -71.80M | 567.00K | -27.68M |
| Shares Outstanding (Basic) | 44.68M | 44.26M | 9.89M | 1.93M | 1.44M |
| Shares Outstanding (Diluted) | 44.68M | 44.26M | 9.89M | 2.18M | 1.44M |
| EPS (Basic) | -0.54 | -1.10 | -7.26 | 0.29 | -19.26 |
| EPS (Diluted) | -0.54 | -1.10 | -7.26 | 0.29 | -19.26 |
| Free Cash Flow | 105.10M | 109.67M | -69.57M | -41.60M | -24.59M |
| Free Cash Flow Per Share | 2.35 | 2.48 | -7.03 | -19.11 | -17.11 |
| Gross Margin | 100.00% | 100.00% | 100.00% | 100.00% | |
| Operating Margin | -56.68% | -175.83% | -7,518.42% | -30,165.56% | |
| Profit Margin | -24.51% | -106.37% | -6,678.88% | 375.50% | |
| Free Cash Flow Margin | 106.29% | 238.67% | -6,471.91% | -27,550.33% | |
| EBITDA | -54.40M | -79.19M | -79.42M | -44.70M | -27.39M |
| EBITDA Margin | -55.01% | -172.34% | |||
| D&A For EBITDA | 1.65M | 1.60M | 1.40M | 848.00K | 577.00K |
| EBIT | -56.05M | -80.80M | -80.82M | -45.55M | -27.97M |
| EBIT Margin | -56.68% | -175.83% | |||
| Effective Tax Rate | 14.19% |
Balance sheet
Fiscal year January - December; amounts in USD.
| TTM | FY2025 | FY2024 | FY2023 | FY2022 | |
|---|---|---|---|---|---|
| Cash & Equivalents | 84.66M | 120.72M | 238.20M | 88.48M | 30.61M |
| Short-Term Investments | 287.66M | 270.37M | 112.73M | ||
| Cash & Short-Term Investments | 372.32M | 391.09M | 350.92M | 88.48M | 30.61M |
| Accounts Receivable | 12.16M | 10.36M | 171.00K | 151.00K | |
| Other Receivables | 3.78M | 3.38M | 953.00K | 22.62M | |
| Receivables | 15.94M | 13.74M | 1.12M | 22.78M | |
| Prepaid Expenses | 7.76M | 4.98M | 4.54M | 1.33M | 1.08M |
| Other Current Assets | 133.00K | 1.15M | 239.00K | 92.00K | 204.00K |
| Total Current Assets | 396.15M | 410.96M | 356.82M | 112.68M | 31.89M |
| Property, Plant & Equipment | 24.26M | 25.93M | 28.69M | 17.19M | 3.10M |
| Long-Term Investments | 144.19M | 157.57M | 69.87M | ||
| Other Long-Term Assets | 2.13M | 1.72M | 1.17M | 1.00M | 1.12M |
| Total Assets | 566.74M | 596.19M | 456.55M | 130.87M | 36.12M |
| Accounts Payable | 3.97M | 10.28M | 3.20M | 2.64M | 3.07M |
| Accrued Expenses | 11.70M | 12.02M | 7.72M | 3.99M | 1.71M |
| Current Portion of Leases | 2.41M | 2.21M | 1.85M | 710.00K | |
| Current Income Taxes Payable | 788.00K | 200.00K | |||
| Current Unearned Revenue | 60.35M | 62.27M | |||
| Other Current Liabilities | 95.00K | 148.00K | 78.00K | 85.00K | 50.00K |
| Total Current Liabilities | 79.32M | 86.93M | 12.85M | 6.91M | 5.54M |
| Long-Term Leases | 20.14M | 21.41M | 23.62M | 12.57M | |
| Long-Term Unearned Revenue | 80.04M | 105.92M | |||
| Other Long-Term Liabilities | 521.00K | 33.00K | 546.00K | 83.00K | |
| Total Liabilities | 180.02M | 214.26M | 36.51M | 20.03M | 5.63M |
| Common Stock | 46.00K | 45.00K | 44.00K | 3.00K | 3.00K |
| Additional Paid-In Capital | 576.86M | 548.52M | 538.32M | 8.20M | 6.55M |
| Retained Earnings | -188.92M | -167.25M | -118.37M | -46.58M | -50.76M |
| Comprehensive Income & Other | -1.26M | 617.00K | 56.00K | ||
| Total Common Equity | 386.72M | 381.93M | 420.05M | -38.37M | -44.20M |
| Shareholders' Equity | 386.72M | 381.93M | 420.05M | 110.84M | 30.49M |
| Total Liabilities & Equity | 566.74M | 596.19M | 456.55M | 130.87M | 36.12M |
| Total Debt | 22.55M | 23.62M | 25.48M | 12.57M | 710.00K |
| Net Cash (Debt) | 493.97M | 525.03M | 395.31M | 75.92M | 29.90M |
| Net Cash Per Share | 11.06 | 11.86 | 39.97 | 34.87 | 20.81 |
| Filing Date Shares Outstanding | 46.68M | 44.91M | 44.44M | 3.16M | 1.44M |
| Total Common Shares Outstanding | 45.67M | 44.81M | 44.42M | 3.17M | 1.44M |
| Working Capital | 316.84M | 324.03M | 343.98M | 105.76M | 26.35M |
| Book Value Per Share | 8.47 | 8.52 | 9.46 | -12.11 | -30.76 |
| Tangible Book Value | 386.72M | 381.93M | 420.05M | -38.37M | -44.20M |
| Tangible Book Value Per Share | 8.47 | 8.52 | 9.46 | -12.11 | -30.76 |
| Machinery | 8.38M | 7.96M | 7.30M | 5.90M | 3.20M |
| Construction In Progress | 107.00K | ||||
| Leasehold Improvements | 717.00K | 717.00K | 717.00K | 389.00K |
Cash flow statement
Fiscal year January - December; amounts in USD.
| TTM | FY2025 | FY2024 | FY2023 | FY2022 | |
|---|---|---|---|---|---|
| Net Income | -24.24M | -48.88M | -71.80M | 4.18M | -27.68M |
| Depreciation & Amortization | 1.65M | 1.60M | 1.40M | 848.00K | 577.00K |
| Loss (Gain) From Sale of Assets | -12.50M | -12.50M | -47.62M | ||
| Stock-Based Compensation | 16.28M | 8.48M | 3.15M | 1.62M | 1.52M |
| Other Operating Activities | -1.19M | -1.29M | -473.00K | 1.33M | 530.00K |
| Change in Accounts Receivable | -12.01M | -10.19M | -20.00K | -151.00K | |
| Change in Accounts Payable | -2.58M | 6.60M | 723.00K | -653.00K | 1.73M |
| Change in Unearned Revenue | 140.40M | 168.19M | |||
| Change in Other Net Operating Assets | -532.00K | -1.83M | -455.00K | 1.73M | 20.00K |
| Operating Cash Flow | 106.01M | 110.19M | -67.47M | -38.72M | -23.30M |
| Capital Expenditures | -910.00K | -518.00K | -2.10M | -2.88M | -1.29M |
| Sale of Property, Plant & Equipment | 12.50M | 12.50M | 22.62M | 25.00M | |
| Investment in Securities | -240.69M | -241.33M | -181.12M | ||
| Investing Cash Flow | -229.10M | -229.35M | -160.60M | 22.12M | -1.29M |
| Issuance of Common Stock | 18.44M | 1.69M | 331.25M | 82.00K | |
| Repurchase of Common Stock | -1.00K | -1.00K | -1.00K | -1.00K | |
| Other Financing Activities | -28.41M | ||||
| Financing Cash Flow | 18.44M | 1.69M | 377.78M | 74.52M | 30.05M |
| Net Cash Flow | -104.65M | -117.47M | 149.71M | 57.92M | 5.46M |
| Free Cash Flow | 105.10M | 109.67M | -69.57M | -41.60M | -24.59M |
| Free Cash Flow Margin | 106.29% | 238.67% | -6,471.91% | -27,550.33% | |
| Free Cash Flow Per Share | 2.35 | 2.48 | -7.03 | -19.11 | -17.11 |
| Levered Free Cash Flow | 29.54M | 18.81M | -25.69M | -49.71M | |
| Unlevered Free Cash Flow | 29.54M | 18.81M | -25.69M | -49.71M | |
| Cash Income Tax Paid | 232.00K | 75.00K | |||
| Change in Working Capital | 125.28M | 162.78M | 248.00K | 926.00K | 1.75M |
Ratios
Fiscal year January - December; amounts in USD.
| TTM | FY2025 | FY2024 | FY2023 | FY2022 | |
|---|---|---|---|---|---|
| Market Capitalization | 1.99B | 1.25B | 1.02B | ||
| Enterprise Value | 1.49B | 710.86M | 1.13B | ||
| Last Close Price | 44.00 | 27.88 | 22.90 | ||
| Forward PE | 16.99 | ||||
| PS Ratio | 20.39 | 27.17 | 945.88 | ||
| PB Ratio | 5.20 | 3.27 | 2.42 | ||
| P/TBV Ratio | 5.21 | 3.27 | 2.42 | ||
| P/FCF Ratio | 19.18 | 11.38 | |||
| P/OCF Ratio | 19.02 | 11.33 | |||
| EV/Sales Ratio | 15.40 | 15.47 | 1,049.95 | ||
| EV/FCF Ratio | 14.48 | 6.48 | |||
| Debt / Equity Ratio | 0.06 | 0.06 | 0.06 | 0.11 | 0.02 |
| Debt / FCF Ratio | 0.21 | 0.21 | |||
| Net Debt / Equity Ratio | -1.28 | -1.38 | -0.94 | -0.69 | -0.98 |
| Net Debt / EBITDA Ratio | 9.08 | 6.63 | 4.98 | 1.70 | 1.09 |
| Net Debt / FCF Ratio | -4.70 | -4.79 | 5.68 | 1.82 | 1.22 |
| Asset Turnover | 0.20 | 0.09 | 0.00 | 0.00 | |
| Quick Ratio | 4.89 | 4.66 | 27.40 | 16.09 | 5.52 |
| Current Ratio | 5.00 | 4.73 | 27.77 | 16.30 | 5.75 |
| Return on Equity (ROE) | -6.34% | -12.19% | -27.05% | 5.92% | |
| Return on Assets (ROA) | -7.13% | -9.59% | -17.20% | -34.10% | |
| Return on Invested Capital (ROIC) | -123.05% | -124.80% | -111.92% | ||
| Return on Capital Employed (ROCE) | -11.50% | -15.90% | -18.20% | -36.70% | -91.50% |
| Earnings Yield | -1.28% | -3.92% | -7.06% | ||
| FCF Yield | 5.21% | 8.79% | -6.84% | ||
| Buyback Yield / Dilution | -45.19% | -347.45% | -354.32% | -51.52% |