NASDAQ : PTGX
Protagonist Therapeutics, Inc. — Financial statements
Healthcare · Biotechnology · United States
Last price 144.85 USD (Oct 30, 2026, 4:00 PM EDT) · Market cap 9.37B
Overview · Financial statements · Key statistics · Dividends · Company profile · Price history · Reports
Financial statements
Protagonist Therapeutics, Inc. (PTGX) reported revenue of 281.99M USD (TTM). Five years of income statement, balance sheet, cash flow and ratios below.
Income statement
Fiscal year January - December; amounts in USD.
| TTM | FY2025 | FY2024 | FY2023 | FY2022 | FY2021 | |
|---|---|---|---|---|---|---|
| Revenue | 281.99M | 46.02M | 434.43M | 60.00M | 26.58M | 27.36M |
| Gross Profit | 281.99M | 46.02M | 434.43M | 60.00M | 26.58M | 27.36M |
| Selling, General & Admin | 48.49M | 44.85M | 43.46M | 33.49M | 31.74M | 27.20M |
| Research & Development | 175.16M | 159.29M | 138.13M | 120.16M | 126.22M | 126.01M |
| Operating Expenses | 223.65M | 204.14M | 181.59M | 153.65M | 157.95M | 153.20M |
| Operating Income | 58.34M | -158.13M | 252.84M | -93.65M | -131.37M | -125.84M |
| Interest & Investment Income | 26.11M | 28.79M | 26.32M | 14.90M | 4.06M | 443.00K |
| Currency Exchange Gain (Loss) | -80.00K | -149.00K | ||||
| Other Non Operating Income (Expenses) | -129.00K | 27.00K | 250.00K | -201.00K | ||
| EBT Excluding Unusual Items | 84.33M | -129.31M | 279.41M | -78.95M | -127.39M | -125.55M |
| Pretax Income | 84.34M | -129.31M | 279.41M | -78.95M | -127.39M | -125.55M |
| Income Tax Expense | 1.43M | 838.00K | 4.22M | |||
| Net Income | 82.91M | -130.15M | 275.19M | -78.95M | -127.39M | -125.55M |
| Net Income to Common | 82.91M | -130.15M | 275.19M | -78.95M | -127.39M | -125.55M |
| Shares Outstanding (Basic) | 64.71M | 63.57M | 61.57M | 56.76M | 49.04M | 46.32M |
| Shares Outstanding (Diluted) | 67.36M | 63.57M | 65.08M | 56.76M | 49.04M | 46.32M |
| EPS (Basic) | 1.28 | -2.05 | 4.47 | -1.39 | -2.60 | -2.71 |
| EPS (Diluted) | 1.22 | -2.05 | 4.23 | -1.39 | -2.60 | -2.71 |
| Free Cash Flow | 130.58M | 56.08M | 182.80M | -70.84M | -108.93M | -108.97M |
| Free Cash Flow Per Share | 1.94 | 0.88 | 2.81 | -1.25 | -2.22 | -2.35 |
| Gross Margin | 100.00% | 100.00% | 100.00% | 100.00% | 100.00% | 100.00% |
| Operating Margin | 20.69% | -343.63% | 58.20% | -156.09% | -494.24% | -460.01% |
| Profit Margin | 29.40% | -282.83% | 63.34% | -131.59% | -479.26% | -458.94% |
| Free Cash Flow Margin | 46.31% | 121.87% | 42.08% | -118.08% | -409.81% | -398.31% |
| EBITDA | 59.88M | -156.85M | 253.67M | -92.67M | -130.34M | -125.03M |
| EBITDA Margin | 21.24% | 58.39% | -154.46% | |||
| D&A For EBITDA | 1.54M | 1.28M | 826.00K | 977.00K | 1.03M | 813.00K |
| EBIT | 58.34M | -158.13M | 252.84M | -93.65M | -131.37M | -125.84M |
| EBIT Margin | 20.69% | 58.20% | -156.09% | |||
| Effective Tax Rate | 1.69% | 1.51% |
Balance sheet
Fiscal year January - December; amounts in USD.
| TTM | FY2025 | FY2024 | FY2023 | FY2022 | FY2021 | |
|---|---|---|---|---|---|---|
| Cash & Equivalents | 420.08M | 128.39M | 97.25M | 186.73M | 125.74M | 123.67M |
| Short-Term Investments | 362.50M | 438.97M | 321.66M | 154.89M | 111.61M | 203.24M |
| Cash & Short-Term Investments | 782.58M | 567.36M | 418.91M | 341.62M | 237.35M | 326.90M |
| Accounts Receivable | 16.78M | 121.00K | 165.00M | 10.00M | 10.00K | 1.57M |
| Other Receivables | 2.86M | 4.38M | 3.49M | 332.00K | 42.00K | 3.77M |
| Receivables | 19.64M | 4.50M | 168.49M | 10.33M | 52.00K | 5.33M |
| Prepaid Expenses | 2.62M | 5.71M | 4.24M | 3.63M | 5.67M | 8.50M |
| Other Current Assets | 2.31M | |||||
| Total Current Assets | 807.15M | 577.57M | 591.64M | 355.58M | 243.08M | 340.74M |
| Property, Plant & Equipment | 10.40M | 11.69M | 12.61M | 2.15M | 4.63M | 6.73M |
| Long-Term Investments | 66.88M | 78.64M | 140.25M | |||
| Other Long-Term Assets | 1.12M | 287.00K | 225.00K | 225.00K | 225.00K | 225.00K |
| Total Assets | 885.54M | 668.19M | 744.73M | 357.95M | 247.93M | 347.69M |
| Accounts Payable | 3.46M | 5.34M | 1.61M | 772.00K | 3.64M | 1.60M |
| Accrued Expenses | 21.49M | 28.08M | 23.62M | 19.26M | 24.54M | 37.31M |
| Current Portion of Leases | 2.40M | 2.28M | 510.00K | 1.14M | 2.52M | 2.20M |
| Current Income Taxes Payable | 2.69M | |||||
| Current Unearned Revenue | 9.66M | 9.55M | 18.89M | 1.60M | ||
| Other Current Liabilities | 175.00K | 185.00K | 74.00K | 102.00K | 484.00K | 1.31M |
| Total Current Liabilities | 37.18M | 45.44M | 47.40M | 21.27M | 31.18M | 44.02M |
| Long-Term Leases | 6.82M | 8.04M | 10.36M | 1.14M | 3.66M | |
| Long-Term Unearned Revenue | 11.68M | |||||
| Total Liabilities | 44.00M | 53.48M | 69.43M | 21.27M | 32.32M | 47.67M |
| Common Stock | 1.00K | 1.00K | 1.00K | 1.00K | ||
| Additional Paid-In Capital | 1.15B | 1.08B | 1.02B | 952.49M | 752.72M | 709.68M |
| Retained Earnings | -304.04M | -470.67M | -340.52M | -615.71M | -536.75M | -409.36M |
| Comprehensive Income & Other | -828.00K | 641.00K | -82.00K | -105.00K | -359.00K | -299.00K |
| Total Common Equity | 841.54M | 614.71M | 675.29M | 336.68M | 215.61M | 300.02M |
| Shareholders' Equity | 841.54M | 614.71M | 675.29M | 336.68M | 215.61M | 300.02M |
| Total Liabilities & Equity | 885.54M | 668.19M | 744.73M | 357.95M | 247.93M | 347.69M |
| Total Debt | 9.22M | 10.32M | 10.87M | 1.14M | 3.66M | 5.86M |
| Net Cash (Debt) | 840.24M | 635.68M | 548.30M | 340.48M | 233.70M | 321.04M |
| Net Cash Per Share | 12.47 | 10.00 | 8.43 | 6.00 | 4.77 | 6.93 |
| Filing Date Shares Outstanding | 64.71M | 63.81M | 61.38M | 58.27M | 51.28M | 48.41M |
| Total Common Shares Outstanding | 64.67M | 62.58M | 61.04M | 57.71M | 49.34M | 47.84M |
| Working Capital | 769.97M | 532.13M | 544.24M | 334.30M | 211.90M | 296.72M |
| Book Value Per Share | 13.01 | 9.82 | 11.06 | 5.83 | 4.37 | 6.27 |
| Tangible Book Value | 841.54M | 614.71M | 675.29M | 336.68M | 215.61M | 300.02M |
| Tangible Book Value Per Share | 13.01 | 9.82 | 11.06 | 5.83 | 4.37 | 6.27 |
| Machinery | 9.64M | 9.24M | 7.80M | 6.47M | 5.91M | 5.18M |
| Leasehold Improvements | 2.94M | 2.94M | 2.42M | 963.00K | 913.00K | 877.00K |
Cash flow statement
Fiscal year January - December; amounts in USD.
| TTM | FY2025 | FY2024 | FY2023 | FY2022 | FY2021 | |
|---|---|---|---|---|---|---|
| Net Income | 82.91M | -130.15M | 275.19M | -78.95M | -127.39M | -125.55M |
| Depreciation & Amortization | 1.54M | 1.28M | 2.90M | 3.31M | 3.37M | 2.77M |
| Loss (Gain) From Sale of Investments | -5.09M | -7.22M | -8.88M | -4.57M | -549.00K | 1.83M |
| Stock-Based Compensation | 49.82M | 45.97M | 37.55M | 29.29M | 24.20M | 16.39M |
| Other Operating Activities | 1.32M | 1.58M | 194.00K | |||
| Change in Accounts Receivable | 5.50M | 164.88M | -155.00M | -9.99M | 1.56M | 860.00K |
| Change in Accounts Payable | 214.00K | 3.72M | 842.00K | -2.87M | 2.04M | -1.39M |
| Change in Unearned Revenue | -10.40M | -21.02M | 30.57M | -1.60M | -12.88M | |
| Change in Income Taxes | -2.69M | 2.69M | ||||
| Change in Other Net Operating Assets | 5.39M | 1.31M | -1.71M | -6.65M | -9.77M | 10.09M |
| Operating Cash Flow | 131.20M | 57.67M | 184.15M | -70.24M | -108.14M | -107.86M |
| Capital Expenditures | -615.00K | -1.59M | -1.35M | -609.00K | -795.00K | -1.10M |
| Investment in Securities | 79.34M | -47.74M | -298.13M | -38.65M | 92.26M | -14.76M |
| Investing Cash Flow | 78.72M | -49.33M | -299.48M | -39.26M | 91.47M | -15.86M |
| Issuance of Common Stock | 41.61M | 23.34M | 26.45M | 171.25M | 19.00M | 130.11M |
| Repurchase of Common Stock | -479.00K | -600.00K | -769.00K | -188.00K | -189.00K | |
| Other Financing Activities | 25.00K | |||||
| Financing Cash Flow | 41.61M | 22.86M | 25.85M | 170.48M | 18.84M | 129.92M |
| Foreign Exchange Rate Adjustments | -90.00K | -126.00K | ||||
| Net Cash Flow | 251.53M | 31.20M | -89.48M | 60.98M | 2.08M | 6.07M |
| Free Cash Flow | 130.58M | 56.08M | 182.80M | -70.84M | -108.93M | -108.97M |
| Free Cash Flow Margin | 46.31% | 121.87% | 42.08% | -118.08% | -409.81% | -398.31% |
| Free Cash Flow Per Share | 1.94 | 0.88 | 2.81 | -1.25 | -2.22 | -2.35 |
| Levered Free Cash Flow | 96.15M | 105.62M | 65.11M | -43.31M | -60.37M | -61.59M |
| Unlevered Free Cash Flow | 96.15M | 105.62M | 65.11M | -43.31M | -60.37M | -61.59M |
| Cash Income Tax Paid | 3.69M | 3.69M | 1.53M | |||
| Change in Working Capital | 705.00K | 146.21M | -122.61M | -19.51M | -7.77M | -3.31M |
Ratios
Fiscal year January - December; amounts in USD.
| TTM | FY2025 | FY2024 | FY2023 | FY2022 | FY2021 | |
|---|---|---|---|---|---|---|
| Market Capitalization | 9.23B | 5.46B | 2.30B | 1.32B | 536.75M | 1.63B |
| Enterprise Value | 8.39B | 4.79B | 1.73B | 1.00B | 273.55M | 1.29B |
| Last Close Price | 144.85 | 87.34 | 38.60 | 22.93 | 10.91 | 34.20 |
| PE Ratio | 116.82 | 8.36 | ||||
| Forward PE | 67.16 | 59.76 | 36.33 | |||
| PS Ratio | 33.24 | 118.66 | 5.29 | 22.04 | 20.19 | 59.67 |
| PB Ratio | 11.13 | 8.88 | 3.41 | 3.93 | 2.49 | 5.44 |
| P/TBV Ratio | 11.14 | 8.88 | 3.41 | 3.93 | 2.49 | 5.44 |
| P/FCF Ratio | 71.78 | 97.36 | 12.59 | |||
| P/OCF Ratio | 71.44 | 94.68 | 12.49 | |||
| EV/Sales Ratio | 30.26 | 104.14 | 3.98 | 16.69 | 10.29 | 47.01 |
| EV/EBITDA Ratio | 142.49 | 6.81 | ||||
| EV/EBIT Ratio | 146.25 | 6.83 | ||||
| EV/FCF Ratio | 65.34 | 85.45 | 9.45 | |||
| Debt / Equity Ratio | 0.01 | 0.02 | 0.02 | 0.00 | 0.02 | 0.02 |
| Debt / EBITDA Ratio | 0.15 | 0.04 | ||||
| Debt / FCF Ratio | 0.07 | 0.18 | 0.06 | |||
| Net Debt / Equity Ratio | -1.00 | -1.03 | -0.81 | -1.01 | -1.08 | -1.07 |
| Net Debt / EBITDA Ratio | -14.03 | 4.05 | -2.16 | 3.67 | 1.79 | 2.57 |
| Net Debt / FCF Ratio | -6.43 | -11.34 | -3.00 | 4.81 | 2.15 | 2.95 |
| Asset Turnover | 0.35 | 0.07 | 0.79 | 0.20 | 0.09 | 0.08 |
| Quick Ratio | 21.58 | 12.59 | 12.39 | 16.54 | 7.61 | 7.55 |
| Current Ratio | 21.71 | 12.71 | 12.48 | 16.71 | 7.80 | 7.74 |
| Return on Equity (ROE) | 10.98% | -20.18% | 54.39% | -28.59% | -49.41% | -43.32% |
| Return on Assets (ROA) | 4.55% | -13.99% | 28.66% | -19.32% | -27.57% | -23.40% |
| Return on Invested Capital (ROIC) | 61.79% | -97.34% | 93.18% | |||
| Return on Capital Employed (ROCE) | 6.90% | -25.40% | 36.30% | -27.80% | -60.60% | -41.40% |
| Earnings Yield | 0.86% | -2.38% | 11.96% | -5.97% | -23.73% | -7.69% |
| FCF Yield | 1.39% | 1.03% | 7.95% | -5.36% | -20.29% | -6.68% |
| Buyback Yield / Dilution | -4.05% | 2.31% | -14.65% | -15.74% | -5.87% | -34.67% |