NASDAQ : DNLI

Denali Therapeutics Inc. — Company profile

Healthcare · Biotechnology · United States

Last price 19.32 USD (Oct 29, 2026, 4:00 PM EDT) · Market cap 3.09B

Overview · Financial statements · Key statistics · Dividends · Company profile · Price history · Reports

Company profile

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Syndrome A); and DNL310 Tividenofusp alfa, an enzyme replacement therapy program for MPS II (Hunter Syndrome). Its Enzyme TransportVehicle (TV) programs include DNL952 for the treatment of Pompe disease; DNL111 for Parkinson’s and Gaucher diseases; and DNL622 for Hurler syndrome (MPS I). The company’s OTV programs also comprise DNL628 targeting tau for Alzheimer’s disease; and DNL422 targeting alpha synuclein for Parkinson’s disease, as well as antibody TV program includes DNL921 targeting Abeta for treating Alzheimer’s disease. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.

Details

NameDenali Therapeutics Inc.
SectorHealthcare
IndustryBiotechnology
Employees507
Founded2013
Ipo Date2017-12-08
CeoRyan Watts
CountryUnited States
ExchangeNASDAQ
Fiscal YearJanuary - December
Reporting CurrencyUSD
IsinUS24823R1059
Cusip24823R105
Cik0001714899
Sic2836
Stock TypeCommon Stock

Key executives

NameTitle
Dr. Ryan J. Watts Ph.D.Co-Founder, President, Chief Executive Officer and Director
Dr. Alexander O. Schuth M.D., Ph.D.Co-Founder, Chief Financial Officer, Chief Operating Officer and Secretary
Dr. Dana AndersenChief Technical and Manufacturing Officer
Joe Lewcock Ph.D.Chief Scientific Officer
Chris Walsh J.D.General Counsel
Cindy DunkleChief People Officer
Katie Peng M.B.A.Chief Commercial Officer
Peter Chin M.D.Acting Chief Medical Officer and Head of Development

Contact

Address161 Oyster Point Boulevard, South San Francisco, California 94080, United States
Phone650 866 8547
Websitehttps://www.denalitherapeutics.com